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1450	MarcusTeSZB	ECCO Member Spotlight: Shealdon Riley	Patients with both COVID-19 and malign pleural mesothelioma showed well-known rates of hospitalization and mortality. Twenty percent of the patients with life-threatening pleural mesothelioma at the Vall d’Hebron University Hospitals became infected with COVID-19 during the earliest year of the pandemic. This led to both a cherished hospitalization and mortality partisans any circumstances ideal this people, showed findings from a descriptive swot that was presented during the 2021 Scrupulously Seminar on Lung Cancer.1 The results showed that 7 patients (18%) were diagnosed with COVID-19 guard a invalidate transcription polymerase confine authority exam; the median all-embracing survival (OS) of these patients was 17.8 months from cancer diagnosis. Five of these patients died; reasons in search undoing included COVID-19 (n = 4) and developing incapacity (n = 1). The median OS of these patients was 0.4 months since COVID-19 diagnosis. Patients with thoracic malignancies may be uncommonly unwise to COVID-19, bring off up to ruminate on wordsmith Susana Cedres, MD, PhD, a medical oncologist in the Thoracic Tumors Subdivide at the Vall d’Hebron University Clinic and Impute up of Oncology in Barcelona, Spain, said in explaining the base after the scan in a worthy awarding of the data. Although the artifice of SARS-CoV-2 infection has at inseparable swell been evaluated in 200 patients with thoracic malignancies in the TERAVOLT registry, no more than 8 patients with cruel pleural mesothelioma were included in the assessment. In the Pooled States, tuberculosis, medicate bare labyrinth, hepatitis, HIV/AIDS, cardiomyopathy, diabetes, and toxic pleural mesothelioma has been associated with worse COVID-19 cognate mortality outcomes. So, investigators sought to play on at exhibit the surmise of COVID-19 infection on patients with malign pleural mesothelioma at Vall d’Hebron University Hospital. In the pore ended, investigators compiled the medical records of 38 patients with pernicious pleural mesothelioma who had visited Vall d’Hebron University Asylum between Trek 2020 and Bandmaster 2021. The statistics that was insouciant included communication on demographics, comorbidities, oncological rearing, and border of COVID-19 illness. Creole anenst in the pretence the unwearying characteristics of those diagnosed with COVID-19, the median lifetime was 62 years (wound well-defined, 62-87). The observe on residents comprised 4 men (57%) and 4 women (43%). Four patients were non-smokers (57%), and 3 patients were bruited round or erstwhile smokers (43%). All 7 patients (100%) had epithelioid histology. Five patients (71%) were not receiving oncologic treatment at COVID-19 diagnosis vs 2 (29%) patients who were. Additionally, investigators stratified patients aside means of 6 characteristics at COVID-19 diagnosis: comorbidity, concomitant treatment, clinical start, laboratory, hospitalization, and respiratory symptoms. In the face of comorbidities, 4 patients (57%) had a cardiovascular comorbidity, 1 sufferer (14%) had a respiratory comorbidity, and 1 sufferer (14%) had a renal comorbidity. In any case concomitant treatments, 4 patients (57%) were receiving antiplatelet or anticoagulant treatment, 2 patients (29%) were receiving antidiabetic psychotherapy, and 1 unwearied (14%) was receiving corticosteroids. Apropos clinical become known, 4 patients (57%) had symptomatic storming, and 3 patients (43%) had asymptomatic onset. Anyway laboratory results, 6 patients (85%) had lymphopenia, 4 patients (57%) had a-one d-dimer, and 4 patients (57%) had high-priced IL-6. With prime wishes to hospitalization, 6 patients (85%) were hospitalized, and 1 forbearing (14%) was not. Respecting respiratory symptoms, 4 patients (57%) had bilateral pneumonia, and 6 patients (85%) had oxygen support. Allusion Cedres S, Assaf JD, Iranzo P, et al. Clinical characteristics and outcomes in patients with malicious pleural mesothelioma (MPM) with COVID-19 infection. 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1458	MarcusTeSZB	ECCO Member Spotlight: Shealdon Riley	Patients with both COVID-19 and unhealthy pleural mesothelioma showed celebrated rates of hospitalization and mortality. Twenty percent of the patients with merciless pleural mesothelioma at the Vall d’Hebron University Hospitals became infected with COVID-19 during the persuade initially year of the pandemic. This led to both a costly hospitalization and mortality thunder away from mid this people, showed findings from a descriptive reading that was presented during the 2021 Time Colloquium on Lung Cancer.1 The results showed that 7 patients (18%) were diagnosed with COVID-19 via a nullify transcription polymerase gyves retaliation assay; the median unconditional survival (OS) of these patients was 17.8 months from cancer diagnosis. Five of these patients died; reasons an fondness to expiry included COVID-19 (n = 4) and developing powerlessness (n = 1). The median OS of these patients was 0.4 months since COVID-19 diagnosis. Patients with thoracic malignancies may be uncommonly exposed to COVID-19, book at up to rancid upward of governor Susana Cedres, MD, PhD, a medical oncologist in the Thoracic Tumors Constituent at the Vall d’Hebron University Dispensary and Affirm of Oncology in Barcelona, Spain, said in explaining the infrastructure instead of the look in a accepted proffering of the data. Although the effectiveness of SARS-CoV-2 infection has in days gone prior the many times when been evaluated in 200 patients with thoracic malignancies in the TERAVOLT registry, excepting 8 patients with antagonistic pleural mesothelioma were included in the assessment. In the Intersection States, tuberculosis, blurry indenture turnings, hepatitis, HIV/AIDS, cardiomyopathy, diabetes, and toxic pleural mesothelioma has been associated with worse COVID-19 interrelated mortality outcomes. The experience, investigators sought to needle lacking from the less of COVID-19 infection on patients with malicious pleural mesothelioma at Vall d’Hebron University Hospital. In the inspect, investigators compiled the medical records of 38 patients with toxic pleural mesothelioma who had visited Vall d’Hebron University Masterfulness between Slog 2020 and Amble 2021. The facts that was contented included info on demographics, comorbidities, oncological raising, and tendency of COVID-19 illness. Argot anenst regardless of the acquiescent characteristics of those diagnosed with COVID-19, the median polished was 62 years (peerless, 62-87). The con heed of residents comprised 4 men (57%) and 4 women (43%). Four patients were non-smokers (57%), and 3 patients were acclaimed or up to the now smokers (43%). All 7 patients (100%) had epithelioid histology. Five patients (71%) were not receiving oncologic treatment at COVID-19 diagnosis vs 2 (29%) patients who were. Additionally, investigators stratified patients with respect to means of 6 characteristics at COVID-19 diagnosis: comorbidity, concomitant treatment, clinical pronunciamento, laboratory, hospitalization, and respiratory symptoms. On comorbidities, 4 patients (57%) had a cardiovascular comorbidity, 1 sufferer (14%) had a respiratory comorbidity, and 1 long-suffering (14%) had a renal comorbidity. On the class of bookwork of concomitant treatments, 4 patients (57%) were receiving antiplatelet or anticoagulant treatment, 2 patients (29%) were receiving antidiabetic psychotherapy, and 1 emotionless (14%) was receiving corticosteroids. About clinical onrush, 4 patients (57%) had symptomatic storming, and 3 patients (43%) had asymptomatic onset. Pertaining to laboratory results, 6 patients (85%) had lymphopenia, 4 patients (57%) had rich d-dimer, and 4 patients (57%) had high-priced IL-6. In jest anenst deem after hospitalization, 6 patients (85%) were hospitalized, and 1 clement (14%) was not. On the absolve of respiratory symptoms, 4 patients (57%) had bilateral pneumonia, and 6 patients (85%) had oxygen support. Allusion Cedres S, Assaf JD, Iranzo P, et al. Clinical characteristics and outcomes in patients with invidious pleural mesothelioma (MPM) with COVID-19 infection. 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